Analysis

Find orthologs/paralogs for gene symbols across species

Look up the orthologous (or paralogous) gene for up to 50 gene symbols in a target species, via Ensembl's homology-by-symbol REST endpoint. Symbols with no homology record are reported in unmapped, never silently dropped.

post/ortholog_map

Request

  • Base URL: https://seqbench.com/api/v1
  • URL: https://seqbench.com/api/v1/ortholog_map
  • Auth: none required

Request body

symbolsstring[] required

Gene symbols to look up, up to 50 (e.g. ["TP53", "BRCA1"]).

sourceSpeciesstring

Species the symbols belong to: a common name (human, mouse, rat, zebrafish, fruit_fly, worm, yeast, cow, pig, dog, frog, macaque, chimp) or a scientific name such as "rattus_norvegicus". Defaults to "human".

targetSpeciesstring required

Species to find homologs in: a common name (mouse, rat, zebrafish, fruit_fly, worm, yeast, …) or a scientific name such as "danio_rerio".

type'orthologues' | 'paralogues' | 'all'

Homology type to return. Defaults to orthologues.

Response

Tool ran successfully.

okunknown required
toolstring required

The tool slug that ran.

resultobject required

Tool-specific output object. Its shape depends on the tool — call GET /{tool} or see the docs for each tool's fields.

Example response

{
  "provenance": {
    "apiVersion": "1.1.0"
  }
}

Changes

No recorded changes to this operation across all 1 revision of this API.