variants

Query variants

Changed on Nov 6, 2026

Query processed variants with filters and pagination

get/sessions/{session_id}/variants

Request

Base URL
https://api.helena.bio (the document declares no server; this is the origin it was published from)
Auth
none declared
TypeScript
https://skmtc.dev/helena-bioinformatics/apis/helix-insight-variant-analysis-service/docs/sessions/:session_id/variants/get.ts
A function with typed inputs. Its response is checked against the schema.

Path parameters

session_idstring uuid required

Query parameters

acmg_classstring[] nullable

ACMG classifications

min_confidencenumber nullable

min_priority_scorenumber nullable

gene_symbolstring[] nullable

Gene symbols (supports partial match)

consequencestring[] nullable

impactstring[] nullable

Impact levels

max_gnomad_afnumber nullable

include_unknown_afboolean

min_depthinteger nullable

min_qualitynumber nullable

min_vafnumber nullable

max_vafnumber nullable

sv_onlyboolean

Return only rows whose canonical sv_type is non-null

sv_groupstring nullable

sv_querystring nullable

pageinteger

Page number

page_sizeinteger

Results per page

sort_bystring

Sort column

sort_orderstring

Sort order (ASC/DESC)

chromosomestring[] nullable

variant_typestring[] nullable

genotypestring[] nullable

inheritance_modestring[] nullable

biotypestring[] nullable

acmg_criterionstring[] nullable

clinvar_significancestring[] nullable

start_positioninteger nullable

end_positioninteger nullable

has_hpoboolean nullable

min_review_starsinteger nullable

quality_statusstring[] nullable

source_filterstring[] nullable

min_genotype_qualitynumber nullable

min_sift_scorenumber nullable

max_sift_scorenumber nullable

min_alphamissense_scorenumber nullable

max_alphamissense_scorenumber nullable

min_metasvm_scorenumber nullable

max_metasvm_scorenumber nullable

min_dann_scorenumber nullable

max_dann_scorenumber nullable

min_phylop100way_vertebratenumber nullable

max_phylop100way_vertebratenumber nullable

min_gerp_rsnumber nullable

max_gerp_rsnumber nullable

min_bayesdel_addaf_scorenumber nullable

max_bayesdel_addaf_scorenumber nullable

min_bayesdel_noaf_scorenumber nullable

max_bayesdel_noaf_scorenumber nullable

min_mpc_scorenumber nullable

max_mpc_scorenumber nullable

min_spliceai_max_scorenumber nullable

max_spliceai_max_scorenumber nullable

min_plinumber nullable

max_plinumber nullable

min_oe_lof_uppernumber nullable

max_oe_lof_uppernumber nullable

min_oe_lofnumber nullable

max_oe_lofnumber nullable

min_mis_znumber nullable

max_mis_znumber nullable

Response

Successful Response

sv_countsobject nullable

variantsobject[] required

List of variants

total_countinteger required

Total number of variants matching filters

pageinteger required

Current page number

page_sizeinteger required

Number of variants per page

total_pagesinteger required

Total number of pages

has_next_pageboolean required

Whether there is a next page

has_previous_pageboolean required

Whether there is a previous page

Example response

{
  "has_next_page": true,
  "has_previous_page": false,
  "page": 1,
  "page_size": 50,
  "total_count": 150,
  "total_pages": 3,
  "variants": [
    {
      "acmg_class": "P",
      "chromosome": "chr7",
      "gene_symbol": "CFTR",
      "position": 117559590,
      "priority_score": 85.3,
      "variant_idx": 42
    }
  ]
}

Changes

Nov 6, 2026cf28590ba149 Revision changes
- breaking
  query request parameter min_depth list-of-types was narrowed by removing types number
- breaking
  for the query request parameter min_depth, the type of property anyOf[subschema #1]/ was specialized from number to integer
- info
  added the new optional query request parameter acmg_criterion
- info
  added the new optional query request parameter biotype
- info
  added the new optional query request parameter chromosome
- info
  added the new optional query request parameter clinvar_significance
- info
  added the new optional query request parameter end_position
- info
  added the new optional query request parameter genotype
- info
  added the new optional query request parameter has_hpo
- info
  added the new optional query request parameter inheritance_mode
- info
  added the new optional query request parameter max_alphamissense_score
- info
  added the new optional query request parameter max_bayesdel_addaf_score
- info
  added the new optional query request parameter max_bayesdel_noaf_score
- info
  added the new optional query request parameter max_dann_score
- info
  added the new optional query request parameter max_gerp_rs
- info
  added the new optional query request parameter max_metasvm_score
- info
  added the new optional query request parameter max_mis_z
- info
  added the new optional query request parameter max_mpc_score
- info
  added the new optional query request parameter max_oe_lof
- info
  added the new optional query request parameter max_oe_lof_upper
- info
  added the new optional query request parameter max_phylop100way_vertebrate
- info
  added the new optional query request parameter max_pli
- info
  added the new optional query request parameter max_sift_score
- info
  added the new optional query request parameter max_spliceai_max_score
- info
  added the new optional query request parameter min_alphamissense_score
- info
  added the new optional query request parameter min_bayesdel_addaf_score
- info
  added the new optional query request parameter min_bayesdel_noaf_score
- info
  added the new optional query request parameter min_dann_score
- info
  added the new optional query request parameter min_genotype_quality
- info
  added the new optional query request parameter min_gerp_rs
- info
  added the new optional query request parameter min_metasvm_score
- info
  added the new optional query request parameter min_mis_z
- info
  added the new optional query request parameter min_mpc_score
- info
  added the new optional query request parameter min_oe_lof
- info
  added the new optional query request parameter min_oe_lof_upper
- info
  added the new optional query request parameter min_phylop100way_vertebrate
- info
  added the new optional query request parameter min_pli
- info
  added the new optional query request parameter min_review_stars
- info
  added the new optional query request parameter min_sift_score
- info
  added the new optional query request parameter min_spliceai_max_score
- info
  added the new optional query request parameter quality_status
- info
  added the new optional query request parameter source_filter
- info
  added the new optional query request parameter start_position
- info
  added the new optional query request parameter variant_type

Operation history