Search Open Targets
Search the Open Targets Platform, which integrates genetics, genomics, drugs and literature to link drug targets to diseases, from Assyro's copy of its latest release: find targets (genes, by symbol or name), diseases and phenotypes (EFO/MONDO terms), drugs (ChEMBL molecules with mechanism of action and highest clinical stage), and direct target-disease associations scored 0.1 or more. For the targets of a disease, search kind "association" with its disease id; for the diseases of a target, kind "association" with the target symbol; for the drugs acting on a target, kind "drug" with the target. Associations come strongest first, with their scores by evidence type (genetic association, somatic mutation, known drug, pathways, literature, expression, animal models). Call read_open_targets_record for a record in full, with a target's or disease's strongest associations.
Request
- Base URLhttps://api.assyro.com
- Authnone declared
Query parameters
Words of a gene, disease or drug name, e.g. "PCSK9", "Alzheimer disease", "evolocumab".
Keep only targets, diseases, drugs or target-disease associations.
A target: an Ensembl gene id ("ENSG00000169174") or approved symbol ("PCSK9").
A disease id as Open Targets writes it, e.g. "EFO_0000305" or "MONDO_0004975" (search kind "disease" to find it).
A ChEMBL id, e.g. "CHEMBL1201583" (search kind "drug" to find it).
Keep associations scored at least this (0 to 1).
Records to return, default 10.
Skip this many results (for paging), default 0.
Response
Matching records.
Changes
No recorded changes to this operation across all 1 revision of this API.