Search ClinVar
Search ClinVar (NCBI), the public archive of human genetic variants and their clinical significance, from Assyro's weekly copy: find variants by gene symbol, condition, dbSNP rsId, part of the variant's HGVS name (e.g. "c.68_69del", "p.Gly12Asp") or free words, and narrow by classification (pathogenic, likely pathogenic, uncertain significance, likely benign, benign, conflicting...), review status stars (0-4: 3 is an expert panel, 4 a practice guideline) or date last evaluated. Each result gives the VCV accession, ClinVar's aggregate germline classification, review status, date last evaluated, genes and conditions. Without words, the best reviewed and most recently evaluated come first. Call read_clinvar_variant for locations on GRCh37/GRCh38, every condition, RCV accessions and somatic classifications.
Request
- Base URLhttps://api.assyro.com
- Authnone declared
Query parameters
Words in the variant name, gene, conditions or identifiers, e.g. "CFTR cystic fibrosis".
An HGNC gene symbol, e.g. "BRCA1".
A condition name or part of one, e.g. "Lynch syndrome".
Part of the variant's HGVS name, in order, e.g. "c.68_69del" or "p.Arg1699Trp".
Keep variants whose aggregate germline classification includes this term.
Keep variants with at least this many review status stars (2: multiple submitters, no conflicts).
A dbSNP id, e.g. "rs80357914".
Last evaluated on or after this date (YYYY-MM-DD).
Last evaluated on or before this date (YYYY-MM-DD).
Variants to return, default 8.
Skip this many results (for paging), default 0.
Response
Matching records.
Changes
No recorded changes to this operation across all 1 revision of this API.