---
title: "Run classification discordance analysis"
method: POST
path: "/sessions/{session_id}/variants/discordance-analysis"
tags: ["discordance"]
---

# Run classification discordance analysis

`POST /sessions/{session_id}/variants/discordance-analysis`

## Request

- Base URL: `https://api.helena.bio` (the document declares no server; this is the origin it was published from)
- URL: `https://api.helena.bio/sessions/{session_id}/variants/discordance-analysis`
- Auth: HTTP bearer
- TypeScript: <https://skmtc.dev/helena-bioinformatics/apis/helix-insight-variant-analysis-service/docs/sessions/:session_id/variants/discordance-analysis/post.ts> (a function with typed inputs; its response is checked against the schema)

Scans classified variants for internal inconsistencies, ClinVar disagreements, predictor conflicts, criteria anomalies, frequency conflicts, constraint mismatches, and inheritance mode issues. Platform admin only. Read-only.

## Path parameters

- `session_id` string, uuid, required

## Request body

- DiscordanceRequest: Optional request body for discordance analysis.
  - `checks` string[], nullable: Specific checks to run. Default: all checks.
  - `max_results_per_check` integer: Max variants per check (per sub-check for criteria anomalies).

## Response `200`

Successful Response

- DiscordanceResponse: Full discordance analysis response.
  - `session_id` string, required
  - `classifier_version_current` string, required
  - `classifier_version_data` string
  - `total_variants_analyzed` integer, required
  - `total_discordances` integer, required
  - `summary` object
  - `format_warnings` string[]
  - `checks` object

## Other responses

- `422`: Validation Error

---

[API](https://skmtc.dev/helena-bioinformatics/apis/helix-insight-variant-analysis-service.md) - [All operations](https://skmtc.dev/helena-bioinformatics/apis/helix-insight-variant-analysis-service/llms.txt) - [OpenAPI document](https://skmtc.dev/helena-bioinformatics/apis/helix-insight-variant-analysis-service/revisions/a800b0b27feb?raw)