---
title: "Authoritative FDA drug label (Structured Product Labeling)."
method: GET
path: "/api/medical/drug-label"
tags: ["medical"]
---

# Authoritative FDA drug label (Structured Product Labeling).

`GET /api/medical/drug-label`

## Request

- Base URL: `https://2s.io`
- URL: `https://2s.io/api/medical/drug-label`
- Auth: API key in header `PAYMENT-SIGNATURE`

Authoritative FDA drug label (Structured Product Labeling). Give a drug name (brand, generic, or substance), or an exact NDC, RxCUI, or SPL set_id, and get back the FDA-approved label split into the sections agents need: boxed warning, indications and usage, dosage and administration, contraindications, warnings, adverse reactions, drug interactions, use in specific populations, pregnancy, mechanism of action, and active/inactive ingredients. Each record also carries identity metadata (brand/generic names, manufacturer, NDCs, RxCUIs, route, DEA schedule, OTC vs prescription) plus a hasBoxedWarning flag. Free, public-domain US government data. Point-in-time public records, not medical advice. Use for prescribing-support, pharmacy, and clinical agents that must read the real label rather than guess it.

## Query parameters

- `drug` string
- `ndc` string
- `rxcui` string
- `setId` string
- `limit` integer
- `trial` 1

## Other responses

- `200` (unresolved $ref)
- `400`: Invalid request — not charged. error.code: BAD_REQUEST or INVALID_PARAM (parameter validation; error.details.issues lists each problem), MALFORMED_JSON, or a request-specific code. Other client errors: 405 METHOD_NOT_ALLOWED (wrong verb; see the Allow header), 413 PAYLOAD_TOO_LARGE.
- `402`: Payment required. Body is the x402 PaymentRequirements envelope with a multi-network accepts array; the per-call price is in accepts[].amount (and on the operation as x-2s-price). Sign for whichever rail you hold USDC on (EIP-3009 for Base, partial SPL transfer for Solana) and retry with the PAYMENT-SIGNATURE header (X-PAYMENT also accepted for v1 clients). Also PAYMENT_SETTLE_FAILED (error envelope) when a verified payment failed to settle: error.details.chargeStatus is "not_charged" (retry with a fresh payment) or "unknown" (the authorization may still settle before its deadline — check it before retrying).
- `429`: Too many requests — RATE_LIMITED: our per-IP / per-payer limiter. Not charged; retry after Retry-After.
- `5XX`: Server-side failure. 500 INTERNAL: unexpected error; quote error.errorId (also the X-2s-Error-Id header). 502 UPSTREAM_UNAVAILABLE (or another UPSTREAM_* code): the data provider failed — composite endpoints refuse unbilled when every source fails. 503 SERVICE_PAUSED: endpoint paused by the operator kill switch, retry after Retry-After; 503 SPEND_CAP: daily upstream budget exhausted. 504 UPSTREAM_TIMEOUT. Not charged.

---

[API](https://skmtc.dev/2s-io/apis/2s-the-most-everything-api.md) · [All operations](https://skmtc.dev/2s-io/apis/2s-the-most-everything-api/llms.txt) · [OpenAPI document](https://skmtc.dev/2s-io/apis/2s-the-most-everything-api/revisions/da4c5caf686e?raw)